mega
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Description:
Molecular evolution statistical analysis and construction of phylogenetic trees
Type: Cask  |  Latest Version: 12.1.2@0  |  Tracked Since: Dec 17, 2025
Links: Homepage  |  formulae.brew.sh
Category: Other
Tags: bioinformatics phylogenetics evolutionary-analysis molecular-biology research
Install: brew install --cask mega
About:
MEGA (Molecular Evolutionary Genetics Analysis) is a comprehensive software suite for conducting statistical analysis of molecular evolution and constructing phylogenetic trees. It provides a user-friendly graphical interface for sophisticated methods including distance estimation, phylogeny reconstruction, and molecular evolution hypothesis testing.
Key Features:
  • Interactive phylogenetic tree construction and visualization
  • Comprehensive evolutionary distance and selection pressure analysis
  • Support for multiple sequence alignment and data editing
  • Hypothesis testing for evolutionary patterns and selection
Use Cases:
  • Reconstructing evolutionary relationships between species or genes
  • Testing molecular evolutionary hypotheses about selection pressures
  • Analyzing genetic divergence and population genetics data
Alternatives:
  • PhyML – Faster maximum likelihood but lacks GUI and comprehensive analysis features
  • FigTree – Tree visualization only, no statistical analysis capabilities
Version History
Detected Version Rev Change Commit
Dec 21, 2025 3:38pm 12.1.2 0 VERSION_BUMP 0867ecab
Dec 17, 2025 1:18am 12.1.2 0 VERSION_BUMP 6a543141