mrbayes ☆
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Description:
Bayesian inference of phylogenies and evolutionary models
Type: Formula  |  Latest Version: 3.2.7a@0  |  Tracked Since: Dec 28, 2025
Links: Homepage  |  formulae.brew.sh
Category: Other
Tags: bioinformatics phylogenetics bayesian evolution science
Install: brew install mrbayes
About:
MrBayes is a Bayesian inference program for phylogenetic analysis using Markov Chain Monte Carlo (MCMC) sampling. It allows researchers to estimate phylogenetic trees and evolutionary parameters from molecular sequence data under a wide range of statistical models. Its main value is providing robust, statistically grounded support for evolutionary relationships, particularly where complex models are needed.
Key Features:
  • Bayesian MCMC sampling for phylogenetic inference
  • Support for diverse data types (DNA, RNA, amino acids, morphological)
  • Extensive model selection including mixed and partitioned models
  • Convergence diagnostics and consensus tree generation
Use Cases:
  • Inferring phylogenetic trees from DNA or protein sequence alignments
  • Testing evolutionary hypotheses using complex substitution models
  • Estimating divergence times under relaxed clock models
Alternatives:
  • PhyloBayes – Uses a different Bayesian algorithm (CAT model) often better for large datasets or compositional heterogeneity
  • RAxML – Faster maximum likelihood alternative, but uses point estimates rather than full Bayesian posterior sampling
Version History
Detected Version Rev Change Commit
Jan 26, 2026 4:27pm 3.2.7a 0 VERSION_BUMP 2d850833
Sep 16, 2025 3:45am 3 VERSION_BUMP 854a1b21
Oct 10, 2024 3:10am 3 VERSION_BUMP 7f2fa758
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