proteinortho ☆
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Description:
Detecting orthologous genes within different species
Type: Formula  |  Tracked Since: Dec 28, 2025
Links: Homepage  |  formulae.brew.sh
Category: Other
Tags: bioinformatics genomics orthology comparative-genomics biology
Install: brew install proteinortho
About:
Proteinortho is a tool designed to detect orthologous genes across multiple species, facilitating comparative genomics. It utilizes a graph-based approach to identify orthologous groups and synteny blocks, providing insights into evolutionary relationships. This software helps researchers understand gene function and conservation by comparing genomic datasets efficiently.
Key Features:
  • Graph-based orthology detection
  • Synteny block identification
  • Support for large-scale genomic datasets
  • Integration with BLAST and other search tools
Use Cases:
  • Identifying conserved genes for drug target discovery
  • Studying evolutionary divergence between species
Alternatives:
  • OrthoFinder – Focuses on phylogenetic tree inference for orthology, often considered faster for very large datasets.
  • InParanoid – Specializes in identifying orthologs between two species, specifically handling in-paralogs.
Version History
Detected Version Rev Change Commit
Sep 15, 2025 7:28am 0 VERSION_BUMP c2330f01
Dec 12, 2024 5:14pm 0 VERSION_BUMP 2e29cb7d
Nov 10, 2024 3:50pm 0 VERSION_BUMP 4486d2b1
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