proteinortho ☆
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Description:
Detecting orthologous genes within different species
Type: Formula  |  Tracked Since: Dec 28, 2025
Links: Homepage  |  formulae.brew.sh
Category: Other
Tags: bioinformatics genomics orthology comparative-genomics biology
Install: brew install proteinortho
About:
Proteinortho is a tool designed to detect orthologous genes across multiple species, facilitating comparative genomics. It utilizes a graph-based approach to identify orthologous groups and synteny blocks, providing insights into evolutionary relationships. This software helps researchers understand gene function and conservation by comparing genomic datasets efficiently.
Key Features:
  • Graph-based orthology detection
  • Synteny block identification
  • Support for large-scale genomic datasets
  • Integration with BLAST and other search tools
Use Cases:
  • Identifying conserved genes for drug target discovery
  • Studying evolutionary divergence between species
Alternatives:
  • OrthoFinder – Focuses on phylogenetic tree inference for orthology, often considered faster for very large datasets.
  • InParanoid – Specializes in identifying orthologs between two species, specifically handling in-paralogs.
Version History
Detected Version Rev Change Commit
Sep 15, 2025 7:28am 0 VERSION_BUMP c2330f01
Dec 12, 2024 5:14pm 0 VERSION_BUMP 2e29cb7d
Nov 10, 2024 3:50pm 0 VERSION_BUMP 4486d2b1
Sep 11, 2024 7:06am 0 VERSION_BUMP 46953055
Aug 2, 2024 5:42pm 0 VERSION_BUMP b6e1aa98
Mar 27, 2023 2:46pm 0 VERSION_BUMP 43412fde
Mar 27, 2023 2:46pm 0 VERSION_BUMP 3b2360ef
Mar 10, 2023 11:05am 0 VERSION_BUMP c0246fe4
Mar 10, 2023 11:05am 0 VERSION_BUMP 3225deec
Jan 4, 2023 5:06pm 0 VERSION_BUMP e257762f
Jan 4, 2023 5:06pm 0 VERSION_BUMP 3ce3aa4b
Dec 14, 2022 1:31am 0 VERSION_BUMP 46c6869f
Dec 14, 2022 1:31am 0 VERSION_BUMP 2eb5c170
Dec 2, 2022 10:27am 0 VERSION_BUMP f4ed475a
Nov 24, 2022 9:05pm 0 VERSION_BUMP 6565056d
Nov 24, 2022 9:05pm 0 VERSION_BUMP 371af93d
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