ropebwt3 ☆
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Description:
BWT construction and search
Type: Formula  |  Tracked Since: Dec 28, 2025
Links: Homepage  |  formulae.brew.sh
Category: Developer tools
Tags: bioinformatics genomics bwt indexing cli
Install: brew install ropebwt3
About:
Ropebwt3 is a high-performance tool for constructing the Burrows-Wheeler Transform (BWT) from large datasets and performing fast pattern searches. It utilizes a rope data structure to efficiently manage memory, enabling the processing of massive genomic sequences. This makes it a valuable asset for bioinformatics pipelines requiring reference-free indexing and alignment.
Key Features:
  • Memory-efficient BWT construction using rope data structures
  • Fast pattern searching (FM-indexing) capabilities
  • Optimized for large-scale genomic data
  • Reference-free indexing
Use Cases:
  • Building indexes for raw sequencing reads
  • Metagenomic classification and assembly
  • Developing custom sequence alignment tools
Alternatives:
  • bwa – BWA is primarily an aligner that uses BWT, whereas ropebwt3 focuses specifically on BWT construction and indexing.
  • fmindex – General library implementations that may lack the specific optimizations for massive datasets found in ropebwt3.
Version History
Detected Version Rev Change Commit
Sep 15, 2025 4:14pm 0 VERSION_BUMP fc4047fb
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