veryfasttree ☆

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Description:
Efficient phylogenetic tree inference for massive taxonomic datasets

Type: Formula | Latest Version: 4@0 | Tracked Since: Dec 28, 2025

Links: Homepage | formulae.brew.sh

Category: Other

Tags: bioinformatics phylogenetics computational-biology tree-inference genomics

Install: brew install veryfasttree

About:
VeryFastTree is a high-performance implementation of the FastTree algorithm, optimized for reconstructing phylogenetic trees from massive multiple sequence alignments. It leverages vectorization and multi-threading to achieve significant speedups over the original tool, enabling rapid analysis of datasets with millions of sequences. This makes it a practical solution for large-scale metagenomic and taxonomic studies.

Key Features:

Optimized for speed and memory efficiency on large datasets
Supports multi-threading to leverage modern multi-core CPUs
Implements FastTree's heuristics for rapid tree inference
Compatible with standard FASTA and PHYLIP alignment formats

Use Cases:

Constructing large phylogenetic trees from metagenomic data
Rapid taxonomic classification of massive sequence collections
Large-scale evolutionary and biodiversity studies

Alternatives:

FastTree – The original implementation; VeryFastTree offers substantial performance improvements while maintaining similar accuracy.
IQ-TREE – A more advanced tool with complex models; VeryFastTree is significantly faster for large datasets but uses simpler heuristics.

Version History

Detected	Version	Rev	Change	Commit
Sep 20, 2024 9:10pm	4	0	NEW	10a044bc
Sep 20, 2024 3:01pm	4	0	VERSION_BUMP	2f9986b3