beast ☆

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Description:
Bayesian Evolutionary Analysis Sampling Trees

Type: Formula | Latest Version: 10.5.0@0 | Tracked Since: Dec 17, 2025

Links: Homepage | formulae.brew.sh

Category: Other

Tags: phylogenetics bayesian evolution bioinformatics mcmc

Install: brew install beast

About:
BEAST is a powerful software platform for Bayesian analysis of molecular sequences. It performs Bayesian Evolutionary Analysis Sampling Trees, allowing researchers to estimate phylogenies and evolutionary parameters directly from genetic data. Its main value is providing statistically robust, time-calibrated evolutionary trees for understanding species divergence and viral transmission dynamics.

Key Features:

Bayesian MCMC inference for phylogenetic trees
Relaxed molecular clock models for dating
Coalescent-based demographic analysis
Extensible through XML configuration
BEAGLE library support for GPU acceleration

Use Cases:

Estimating species divergence times from DNA sequences
Reconstructing viral outbreak transmission pathways
Inferring population demographic history from genetic data

Alternatives:

MrBayes – MrBayes is another Bayesian phylogenetics tool but focuses more on discrete character models and has a different MCMC implementation
PhyloBayes – PhyloBayes specializes in site-heterogeneous substitution models for deep phylogeny, while BEAST excels at time-calibrated analyses

License: LGPL-2.1-or-later

Dependencies: beagle, openjdk

Bottles available for: arm64_tahoe, arm64_sequoia, arm64_sonoma, arm64_ventura, sonoma, ventura, arm64_linux, x86_64_linux

Version History

Detected	Version	Rev	Change	Commit
Oct 10, 2024 2:53am		1	VERSION_BUMP	2334cd65
Sep 29, 2024 4:14am		1	VERSION_BUMP	109d730e