cromwell ☆
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Description:
Workflow Execution Engine using Workflow Description Language
Type: Formula  |  Latest Version: 91@0  |  Tracked Since: Dec 17, 2025
Links: Homepage  |  @broadinstitute  |  formulae.brew.sh
Category: Developer tools
Tags: workflows wdl bioinformatics pipeline automation
Install: brew install cromwell
About:
Cromwell is a scalable workflow execution engine that interprets workflows written in the Workflow Description Language (WDL). It manages the entire lifecycle of a workflow, including task execution, dependency resolution, and data provenance across diverse backends. This tool simplifies complex computational pipelines by abstracting infrastructure details, making it essential for reproducible bioinformatics and scientific computing.
Key Features:
  • Supports both WDL and CWL workflow languages
  • Scalable backend support (Local, SGE, AWS, GCP, Azure)
  • Built-in job monitoring and detailed error reporting
  • REST API for programmatic workflow management
Use Cases:
  • Orchestrating large-scale bioinformatics pipelines
  • Reproducible scientific data processing
  • Managing batch processing jobs in cloud environments
Alternatives:
  • Nextflow – Nextflow uses a Groovy DSL, whereas Cromwell uses WDL/CWL, offering different syntax preferences for pipeline authors.
License: BSD-3-Clause
Dependencies: openjdk
Bottles available for: all
Version History
Detected Version Rev Change Commit
Oct 8, 2025 5:32pm 0 VERSION_BUMP 3171b844
Oct 8, 2025 5:00pm 0 VERSION_BUMP 99f80912
Nov 10, 2024 4:33pm 0 VERSION_BUMP 09340cb7
Sep 13, 2024 2:49am 0 VERSION_BUMP bf4df7b4
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