nextflow
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Description:
Reproducible scientific workflows
Type: Formula  |  Tracked Since: Dec 28, 2025
Links: Homepage  |  @nextflowio  |  formulae.brew.sh
Category: Developer tools
Tags: workflows bioinformatics devops automation reproducibility
Install: brew install nextflow
About:
Nextflow is a reactive workflow framework for data-intensive computational pipelines. It enables scalable and reproducible scientific workflows by leveraging container technologies like Docker and Singularity. Its key value is simplifying complex task orchestration across diverse execution environments, from a local laptop to a massive cloud cluster.
Key Features:
  • Declarative process definition
  • Multi-cloud and HPC executor support
  • Built-in data provenance and reproducibility
  • Containerization integration (Docker, Singularity)
Use Cases:
  • Bioinformatics pipeline automation (e.g., genomics, proteomics)
  • Large-scale scientific data processing
  • Reproducible machine learning model training workflows
Alternatives:
  • Apache Airflow – Airflow is more general-purpose for ETL and scheduling, while Nextflow is specialized for data-driven computational pipelines with a domain-specific language.
  • Snakemake – Snakemake uses Python syntax for rules, whereas Nextflow uses its own Groovy-based DSL for process definition and execution logic.
Version History
Detected Version Rev Change Commit
Sep 17, 2025 7:41pm 1 VERSION_BUMP 9054a0c0
Sep 17, 2025 12:18pm 1 VERSION_BUMP 904f2ebf
Sep 16, 2025 5:29pm 0 VERSION_BUMP 6382139f