snakemake
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Description:
Pythonic workflow system
Type: Formula  |  Latest Version: 9.14.5@0  |  Tracked Since: Nov 27, 2025
Links: Homepage  |  @snakemake  |  formulae.brew.sh
Category: Developer tools
Tags: workflows bioinformatics data-pipeline automation python
Install: brew install snakemake
About:
Snakemake is a workflow management system designed to create reproducible and scalable data analyses. It allows users to define workflows using a Python-based language, automatically managing dependencies and parallelizing tasks. Its standout feature is the ability to scale from single servers to cluster environments without changing workflow definitions.
Key Features:
  • Python-based syntax for easy integration with data science libraries
  • Automatic dependency resolution and task parallelization
  • Scalable from local execution to HPC clusters and cloud environments
  • Built-in support for reproducibility and report generation
Use Cases:
  • Bioinformatics data processing pipelines
  • Large-scale machine learning model training workflows
  • Automated data analysis and visualization pipelines
Alternatives:
  • Nextflow – Groovy-based, strong container support
  • Apache Airflow – Python-based, focused on scheduling and monitoring
  • Luigi – Python-based, simpler dependency management
Version History
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