kraken2
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Description:
Taxonomic sequence classification system
Type: Formula  |  Latest Version: 2.17.1@0  |  Tracked Since: Nov 25, 2025
Links: Homepage  |  formulae.brew.sh
Category: Other
Tags: bioinformatics metagenomics taxonomy classification genomics
Install: brew install kraken2
About:
Kraken2 is a taxonomic sequence classification system that assigns taxonomy labels to metagenomic sequencing reads. It uses a k-mer matching approach against a compact indexed database for extremely fast classification, making it ideal for large-scale metagenomic analysis.
Key Features:
  • Ultra-fast classification using k-mer matching
  • Low memory footprint compared to traditional alignment
  • Comprehensive taxonomic classification from reads
  • Supports custom database creation
Use Cases:
  • Metagenomic sample analysis and microbiome profiling
  • Pathogen detection in clinical samples
  • Environmental microbial community characterization
Alternatives:
  • centrifuge – Similar speed and purpose, uses different indexing strategy
  • diamond – Faster than BLAST but slower than Kraken2, focuses on protein sequences
Version History
Detected Version Rev Change Commit
Nov 25, 2025 12:35am 0 VERSION_BUMP aa066195
Nov 25, 2025 12:01am 0 VERSION_BUMP ae9d20f0
Nov 11, 2025 2:03pm 0 VERSION_BUMP 5a3cf34c