minigraph ☆
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Description:
Proof-of-concept seq-to-graph mapper and graph generator
Type: Formula  |  Tracked Since: Dec 28, 2025
Links: Homepage  |  formulae.brew.sh
Category: Other
Tags: bioinformatics genomics sequence-alignment pangenome graph-analysis
Install: brew install minigraph
About:
Minigraph is a specialized tool for constructing pan-genome graphs from reference sequences and mapping long sequencing reads to these graphs. It uniquely combines graph construction and read mapping into a single efficient pipeline, enabling rapid analysis of genetic variation beyond linear references.
Key Features:
  • Ultra-fast graph construction and read mapping
  • Supports variant-aware pangenome graph structures
  • Optimized for noisy long-read sequencing data
  • Memory-efficient algorithm design
Use Cases:
  • Building pan-genome graphs from assembled genomes
  • Mapping long-read sequences to complex genomic regions
  • Analyzing structural variants across multiple samples
Alternatives:
  • minimap2 – More general-purpose mapper; minigraph is specialized for graph-based alignment
  • vg – More complex graph operations; minigraph focuses on speed and simplicity
Version History
Detected Version Rev Change Commit
Sep 15, 2025 10:38pm 0 VERSION_BUMP f071a63f
Sep 14, 2024 4:08am 0 VERSION_BUMP 07da4a6e
Apr 21, 2024 3:01pm 0 VERSION_BUMP 6ce39b46
Jun 20, 2023 1:02pm 0 VERSION_BUMP 74668dbd
Jun 19, 2023 3:38pm 0 VERSION_BUMP f95be7a1
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