fastga ☆

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Description:
Pairwise whole genome aligner

Type: Formula | Latest Version: 1.3.1@0 | Tracked Since: Dec 17, 2025

Links: Homepage | formulae.brew.sh

Category: Other

Tags: genomics bioinformatics alignment sequence-analysis genetics

Install: brew install fastga

About:
FASTGA is a high-performance pairwise whole genome aligner designed to efficiently align large genomic sequences. It utilizes a seed-and-extend approach optimized for speed and accuracy, making it suitable for comparative genomics. The tool is specifically engineered to handle the scale and complexity of modern genome assemblies.

Key Features:

High-speed alignment algorithms
Optimized for large genome assemblies
Accurate pairwise comparison
Low memory footprint relative to competitors

Use Cases:

Comparative genomics to identify structural variations
Aligning newly sequenced genomes against reference genomes
Genome assembly validation and finishing

Alternatives:

MUMmer – MUMmer is a widely used suite for genome alignment, while FASTGA focuses on specific optimizations for speed and scalability in pairwise tasks.
Minimap2 – Minimap2 is a versatile aligner for long reads and genome assemblies, whereas FASTGA is specialized specifically for whole-genome pairwise alignment.

License: BSD-3-Clause AND MIT

Bottles available for: arm64_tahoe, arm64_sequoia, arm64_sonoma, arm64_ventura, sonoma, ventura, arm64_linux, x86_64_linux

Version History

Detected	Version	Rev	Change	Commit
Sep 13, 2025 6:25pm		0	VERSION_BUMP	36d1caca